博士/见习教授
办公室:科技大厦1211
邮箱: jiajiaxue@mail.buct.edu.cn
电话:010-64434860
Website: https://scholar.google.com/citations?user=dnXt1ZoAAAAJ&hl=en
研究领域:
生物医用材料及组织工程支架的构筑与性能研究,用于药物可控递送、光热治疗、神经再生、骨软骨再生、及创伤修复等组织工程及再生医学领域。主要研究方向如下:
(1)多功能组织工程神经导管的构筑及其用于外周神经损伤的修复;
(2)刚柔复合支架的构筑及其用于中枢神经系统损伤的修复;
(3)多功能有序光热活性支架修复皮肤创伤的应用研究;
(4)骨修复活性材料的可控制备与应用研究。
2010–2015 | 北京化工大学 |
| 工学博士,材料科学与工程学院 |
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2006–2010 | 北京化工大学 |
| 学士,材料科学与工程学院 |
2019–今 | 见习教授,北京化工大学
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2015–2019 | 博士后,佐治亚理工学院 导师:夏幼南教授 研究方向:多功能神经导管用于外周神经缺损的修复,相变材料用于可控药物释放以促进细胞迁移及神经再生 |
2010–2015 | 博士研究生,北京化工大学 导师:张立群教授 博士论文题目:基于明胶的生物基弹性体及纤维膜材料的制备与性能研究 |
2010 | 本科生,北京化工大学 导师:张立群教授 研究方向:基于明胶的生物弹性体及纳米复合材料的制备与性能研究 |
荣誉及获奖
北京化工大学优秀博士论文 2015
北京化工大学优秀博士毕业生 2015
国家奖学金 2014
北京化工大学优秀研究生干部 2014
北京化工大学优秀研究生 2013
北京化工大学优秀研究生 2012
北京化工大学优秀研究生 2010
北京市三好学生 2010
参加学术组织
Materials Research Society 2020-2021
Society for Biomaterials 2020-2021
Chinese Association for Biomaterials 2020-2021
Chinese Society for Cell Biology 2020-2023
Chinese Chemical Society 2021-2024
发表文章列表
目前发表SCI收录文章43篇,其中以第一作者与通讯作者在 Chemical Reviews, Accounts of Chemical Research, Angewandte Chemie, Advanced Functional Materials, Advanced Science, ACS Nano, Biomaterials 等发表23篇,总引用2500余次,ESI高被引论文2篇,引用H指数为20,参与发表英文著作3部,申请中国专利11项(其中2项专利授权)。代表性论文如下:
1. Chunxu Li, Dario Pisignano, Yu Zhao,* and Jiajia Xue,* “Advances in medical applications of additive manufacturing,” Engineering, 2020, 6, 1222-1231.
2. Jiajia Xue, Tong Wu, Jichuan Qiu, and Younan Xia, “Spatiotemporally controlling the release of biological effectors enhances their effects on cell migration and neurite outgrowth,” Small Methods, 2020, 4, 2000125.
3. Jiajia Xue, Tong Wu, Jichuan Qiu, Sarah Rutledge, Michael L. Tanes, and Younan Xia, “Promoting cell migration and neurite extension along uniaxially aligned nanofibers with biomacromolecular particles in a density gradient,” Advanced Functional Materials, 2020, 30, 2002031.
4. Jiajia Xue, Dario Pisignano,* and Younan Xia*, “Maneuvering the migration and differentiation of stem cells with electrospun nanofibers,” Advanced Science, 2020, 7, 2000735.
5. Anthony Donsante,+* Jiajia Xue,+ Kelly M. Poth, Nathan S. Hardcastle, Bruna Diniz, Deirdre M. O’Connor, Younan Xia,* and Nicholas M. Boulis*, “Controlling the release of neurotrophin-3 and chondroitinase ABC enhances the efficacy of nerve guidance conduits,” Advanced Healthcare Materials, 2020, 9, 2000200. (+equal contribution)
6. Jingjing Ye, Xindan Zhang, Wenqi Xie, Min Gong, Meihong Liao, Qinghan Meng, Jiajia Xue,* Rui Shi,* and Liqun Zhang*, “An enzyme-responsive prodrug with inflammation-triggered therapeutic drug release characteristics,” Macromolecular Bioscience 2020, 20, 2000116.
7. Jiajia Xue,+ Tong Wu,+ Yunqian Dai,+ and Younan Xia, “Electrospun nanofibers: Methods, materials, and applications,” Chemical Reviews, 2019, 119, 5298–5415. (+equal contribution, ESI高被引论文)
8. Jiajia Xue, Tong Wu, Jianhua Li, Chunlei Zhu, and Younan Xia, “Promoting the outgrowth of neurites on electrospun microfibers by functionalization with electrosprayed microparticles of fatty acids,” Angewandte Chemie International Edition, 2019, 58, 3948–3951.
9. B. Streeter,+ Jiajia Xue,+ Younan Xia, and Michael E. Davis, “Electrospun nanofiber-based patches for the delivery of cardiac progenitor cells,” ACS Applied Materials and Interfaces, 2019, 11, 18242–18253. (+equal contribution)
10. Jiajia Xue, Chunlei Zhu, Jianhua Li, Haoxuan Li, and Younan Xia, “Integration of phase-change materials with electrospun fibers for promoting neurite outgrowth under controlled release,” Advanced Functional Materials, 2018, 28, 1705563.
11. Tong Wu,+ Jiajia Xue,+ Haoxuan Li, Chunlei Zhu, Xiumei Mo, and Younan Xia, “General method for generating circular gradients of active proteins on nanofiber scaffolds sought for wound closure and related applications,” ACS Applied Materials & Interfaces, 2018, 10, 8536–8545. (+equal contribution)
12. Jiajia Xue, Jingwei Xie, Wenying Liu, and Younan Xia, “Electrospun nanofibers: New concepts, materials, and applications,” Accounts of Chemical Research, 2017, 50, 1976–1987. ESI高被引论文
13. Jiajia Xue, Junyu Yang, Deirdre M O’Connor, Chunlei Zhu, Da Huo, Nicholas M Boulis, and Younan Xia, “Differentiation of bone marrow stem cells into Schwann cells for the promotion of neurite outgrowth on electrospun fibers,” ACS Applied Materials & Interfaces, 2017, 9, 12299–12310.
14. Jiajia Xue, Yuzhao Niu, Min Gong, Rui Shi, Dafu Chen, Liqun Zhang, and Yuri Lvov, “Electrospun microfiber membranes embedded with drug-loaded clay nanotubes for sustained antimicrobial protection,” ACS Nano, 2015, 9, 1600–1612.
15. Jiajia Xue, Min He, Hao Liu, Yuzhao Niu, Aileen Crawford, Phil D Coates, Dafu Chen, Rui Shi, and Liqun Zhang, “Drug loaded homogeneous electrospun PCL/gelatin hybrid nanofiber structures for anti-infective tissue regeneration membranes,” Biomaterials, 2014, 35, 9395–9405.
撰写书籍章节
3. Mingyu Tang, Suting Liu, Zhihui Li, Liqun Zhang, Yunqian Dai,* Jiajia Xue,* “Special techniques and advanced structures” in Metal oxide-based nanofibers and their applications, Elsevier, 2021, in press.
2. Jiajia Xue,* “Nanomaterials Design and Tests for Neural Tissue Engineering”, in Theranostic Bionanomaterials (Eds.: Wenguo Cui and Xin Zhao), Elsevier, 2018.
1. Liqun Zhang* and Jiajia Xue, “Rubber functionalized with halloysite loaded with antioxidants and antibacterials”, in Functional Polymer Composites with Nanoclays (Eds.: Yuri Lvov, Baochun Guo, and Rawil F Fakhrullin), RSC, Cambridge, 2016, pp. 301–328.
专利
11. 薛佳佳,历龙飞,张馨丹,张立群,石锐 “一种用于伤口敷料的复合纳米纤维膜的制备方法及复合纳米纤维膜”,202110210428.9。
10. 薛佳佳,余逸玲,张立群,张馨丹,龚博文,“一种三层结构的神经导管的制备方法及神经导管”,202110075624.X。
9. 薛佳佳,余逸玲,张馨丹,龚博文,张立群,“一种加载梯度密度粒子的神经导管及制备方法”,202110079001.X。
8. 薛佳佳,余逸玲,张馨丹,龚博文,张立群,“一种加载梯度密度粒子的神经导管及制备方法”,202110079001.X。
7. 薛佳佳,张馨丹,张立群,“负载相变材料微粒的纤维创面修复支架及其制备方法和应用,”202010884625.4
6. 薛佳佳,张馨丹,张立群,“一种可光热触发生长因子阶段性释放的人工皮肤材料及其制法和应用,”202010884640.9
5. 张立群,薛佳佳,牛玉昭,“明胶基弹性体生胶、明胶基弹性体纳米复合材料及两者的制备方法,” CN201510065398。
4. 张立群,薛佳佳,宫敏,石锐,田伟,陈大福,“含有埃洛石纳米管载药型引导组织再生膜及其制备方法,” CN201410692643。
3. 石锐,田伟,张立群,薛佳佳,陈大福,“单层及双层聚己内酯基引导组织再生膜及其制备方法,” CN201310745877。
2. 张立群,牛玉昭,薛佳佳,廖美红,“含有埃洛石纳米管载药型弹性体创伤敷料及其制备方法,” ZL201510366367。
1. 张立群,薛佳佳,石锐,田伟,陈大福,“载药型引导组织再生膜及其制备方法,” ZL201310745878。
主持项目
1. 国家自然科学基金面上项目,2021.01–2024.12,主持
2. 国家自然科学基金青年基金,2021.01–2023.12,主持
3. 北京市自然科学基金重点项目,2020.10–2024.10,课题主持
学术会议
12. Jiajia Xue,“中国生物物理学会材料生物学与智能诊疗技术分会青年学者年会暨2020年生物医用材料与技术交叉青年论坛”,宁波,2020年12月,受邀做口头报告。
11. Jiajia Xue,“2020海峡两岸暨港澳生物材料与组织再生青年科学家学术会议(Biomaterials2020)”,东华大学,上海,2020年11月,受邀做口头报告。
10. Jiajia Xue,“武汉市显微外科临床医学研究中心学科交流研讨会”,湖北省武汉市,武汉大学,2019年11月,受邀做口头报告。
9. Jiajia Xue,“北京化工大学青年学者与国家纳米中心青年创新促进会交流会”,北京化工大学,北京,2019年11月,受邀做口头报告。
8. Jiajia Xue and Younan Xia, “Electrospun Nanofibers for Peripheral Nerve Repair,” The Minerals, Metals & Materials Society 2019 Annual Meeting, 美国德克萨斯州,2019年3月,口头报告。
7. Jiajia Xue and Younan Xia, “Integration of Nanofiber-Based Conduits with Bone Marrow Stem Cells for Potential Application in Neural Tissue Engineering,” 2018 MRS Fall Meeting, Oral Presentation and Poster Exhibition, 美国马萨诸塞州,2018年11月,海报展示和口头报告。
6. Jiajia Xue, Chunlei Zhu, Jianhua Li, and Younan Xia, “Integration of Phase-change materials with electrospun fibers for promoting neurite outgrowth under controlled release,” Society for Biomaterials 2018 Annual Meeting, 美国佐治亚州,2018年4月,海报展示和口头报告。
5. Jiajia Xue, Rui Shi, Yuri Lvov, and Liqun Zhang, “Electrospun Nanofiber Membranes for Sustained and Controlled Drug Delivery,” TERMIS-AM Conference, 美国华盛顿特区,2014年12月,海报展示。
4. Jiajia Xue, Rui Shi, and Liqun Zhang, “Drug loaded electrospun hybrid nanofiber structures for anti-infective tissue regeneration membranes,” UK China AMRI 6th Research Workshop: Advanced Materials for Healthcare, 北京市,2014年3月,海报展示。
3. Jiajia Xue, Min He, Rui Shi, and Liqun Zhang, “Drug Loaded Homogeneous Electrospun PCL/gelatin Hybrid Nanofiber Structures for Anti-infective Tissue Regeneration Membranes,” 6th International Conference on Drug Discovery & Therapy, 阿联酋迪拜,2014年2月,海报展示。
2. Jiajia Xue, Rui Shi, and Liqun Zhang, “Antibacterial, in vitro/vivo Biocompatibility and Biodegradability of PCL-based Electrospun Fibers,” The Third Conference on Quality Control of Biomaterials and Tissue Engineering Products (QCBTEP) Adjunct to TERMIS-AP 2013 Annual Meeting. 浙江省乌镇,2013年10月,海报展示。
1. Jiajia Xue and Liqun Zhang, “Preparation and Properties of Gelatin-based Bio-elastomers,” RCUK Bradford Science Bridges China/EPSRC Global Engagements Research Workshop, 四川省成都市,2013年3月,口头报告。