团队负责人

团队负责人

徐福建

教授/博导
材料学院院长
E-mail:xufj@mail.buct.edu.cn

研究领域:
主要从事医用高分子材料应用基础研究,在药物控释载体、抗菌材料以及多糖功能化方面开展了广泛应用基础研究。

1995-1999年,华东理工大学化工系,学士
1999-2002年,中国科学院过程工程研究所生化国家重点实验室,硕士
2002-2003年,美国宾夕法尼亚州立大学(PSU)农业与生物工程系,博士学习
2003-2006年,新加坡国立大学(NUS)化工与生物分子工程系,博士

2007-2009,Lee Kuan Yew Postdoctoral Fellow, Singapore

2009.1-至今北京化工大学材料科学与工程学院教授博士生导师

2014.5-至今生物医用材料北京实验室执行主任

2014.11-2015.6,北京化工大学材料学院生物材料系,主任

2015.7-2019.6,北京化工大学材料学院副院长

2019.7-2020.6北京化工大学材料学院常务副院长

2017.12-2019.10,北京化工大学-中日友好医院生物医学转化工程研究中心主任

2018.10-至今北京化工大学天然高分子医用材料教育部重点实验室主任

2020.7-至今,北京化工大学材料学院院长



Advanced MaterialsJACSBiomaterials等国际期刊发表论文250余篇,受邀为Chemical ReviewsAccounts of Chemical ResearchChemical Society ReviewsProgress in Polymer ScienceProgress in Materials Science期刊撰写综述论文多篇。申请/授权发明专利60余项,多项专利技术成功落地产业化,并作价入股成立多家公司。主持国家重点研发计划、国家自然科学基金重点项目等项目15余项。兼任中国人民***总医院客座教授,国际期刊Biomaterials Science副主编。2012年入选万人计划青年拔尖人才;2013年获得“国家杰出青年科学基金”资助(结题为特优);2014年获得“长江学者奖励计划特聘教授”;2018年入选北京高校卓越青年科学家计划;2021年获批科技部创新人才推进计划重点领域创新团队(生命健康材料创新团队)和万人计划科技创新领军人才。


 

代表性论文:

(1)   Duan, S.; Wu, R.; Xiong, Y.H.; Ren, H.M.; Lei, C.; Zhao, Y.Q.; Zhang, X.Y.; Xu, F.J.* Multifunctional antimicrobial materials: from rational design to biomedical applications. Progress in Materials Science. 2022, 125: 100887

(2)   Zhao, X.; Guo, K.; Zhang, K.; Duan, S.; Chen, M.; Zhao, N.N.*; Xu, F.J.* Orchestrated yolk-shell nanohybrids regulate macrophage polarization and dendritic cell maturation for oncotherapy with augmented antitumor immunity. Advanced Materials. 2022, 34: 2108263

(3)   Zhu, Y.#; Wu, S.#; Sun, Y.; Zou, X.; Zheng, L.; Duan, S.; Wang, J.; Yu, B.R.*; Sui, R.*; Xu, F.J.* Bacteria-targeting photodynamic nanoassemblies for efficient treatment of multidrug-resistant biofilm infected keratitis. Advanced Functional Materials. 2022, 32: 2111066

(4)   Wang, A.; Duan, S.; Ding, X.J.; Zhao, N.; Hu, Y.; Ding, X.*; Xu, F.J.* Bioswitchable antibacterial coatings enable self-sterilization of implantable healthcare dressings. Advanced Functional Materials. 2021, 31(18): 2011165

(5)   Zhang, X.; Yao, D.; Zhao, W.Y.; Zhang, R.; Yu, B.; Ma, G.; Li, Y.*; Hao, D.*; Xu, F.J.* Engineering platelet-rich plasma based dual-network hydrogel as a bioactive wound dressing with potential clinical translational value. Advanced Functional Materials. 2021, 31(8): 2009258

(6)   Wu, S.; Xu, C.; Zhu, Y.; Zheng, L.; Zhang, L.; Hu, Y.; Yu, B.*; Wang, Y.*; Xu, F.J.* Biofilm-sensitive photodynamic nanoparticles for enhanced penetration and antibacterial efficiency. Advanced Functional Materials. 2021, 31(33): 2103591

(7)   Song, H.Q.; Fan, Y.; Hu, Y.*; Cheng, G.*; Xu, F.J.* Polysaccharide-peptide conjugates: a versatile material platform for biomedical applications. Advanced Functional Materials. 2021, 31(6): 2005978

(8)   Liu, Z.; Zhao, X.; Yu, B.; Zhao, N.*; Zhang, C.; Xu, F.J.* Rough carbon-iron oxide nanohybrids for near-infrared-II light responsive synergistic antibacterial therapy. ACS Nano. 2021, 15: 7482-7490.

(9)   Shao, M.; Fan, Y.; Zhang, K.; Hu, Y.*; Xu, F.J.* One nanosystem with potent antibacterial and gene-delivery performances accelerates infected wound healing. Nano Today. 2021, 39: 101224

(10)  Zhao, N.N.; Yan, L.; Xue, J.; Zhang, K.*; Xu, F.J.* Degradable one-dimensional dextran-iron oxide nanohybrids for MRI-guided synergistic gene/photothermal/magnetolytic therapy. Nano Today. 2021, 38: 101118

(11)  Liu, Y.; Yu, B.; Dai, X.; Zhao, N.*; Xu, F.J.* Biomineralized calcium carbonate nanohybrids for mild photothermal heating-enhanced gene therapy. Biomaterials. 2021,274: 120885

(12)  Zheng, L.#; Li, J.#; Yu, M.#; Jia, W.; Duan, S.; Ding, X.; Yu, B.*; Zhang, X.*; Xu, F.J.* Molecular sizes and antibacterial performance relationships of flexible ionic liquid derivatives. Journal of the American Chemical Society. 2020, 142(47): 20257-20269

(13)  Zhao, Y.Q.; Sun, Y.; Zhang, Y.; Ding, X.; Zhao, N.N.; Yu, B.; Zhao, H.; Duan, S.;* Xu, F.J.* Well-defined gold nanorod/polymer hybrid coating with inherent antifouling and photothermal bactericidal properties for treating infected hernia. ACS Nano. 2020, 14(2): 2265-2275

(14)  Liu, J.Y.#; Hu, Y.#; Li, L; Wang, C.; Wang, J.; Li, Y.*; Chen, D.; Ding, X.; Shen, C.*; Xu, F.J.* Biomass-derived multi-layer-structured microparticles for accelerated hemostasis and bone repair. Advanced Science. 2020, 7(22), 2002243

(15)  Qi, Y.#; Liu, Y#; Yu, B.; Hu, Y.; Zhang, N.; Zheng, Y.; Yang, M.*; Xu, F.J.* A lactose-derived CRISPR/Cas9 delivery system for efficient genome editing in vivo to treat orthotopic hepatocellular carcinoma. Advanced Science. 2020, 7(17), 2001424

(16)  Xu, C.#; Hu, W.#; Zhang, N.; Qi, Y.; Nie, J.J.; Zhao, N.; Yu, B.*; Xu, F.J.* Genetically multimodal therapy mediated by one polysaccharides-based supramolecular nanosystem. Biomaterials. 2020, 248, 120031

(17)  Zhao, N.; Yan, L.; Zhao, X.; Chen, X.; Li, A.; Zheng, D.; Zhou, X.; Dai, X.; Xu, F.J.* Versatile types of organic/inorganic nanohybrids: from strategic design to biomedical applications. Chemical Reviews. 2019, 119(3): 1666-1762

(18)  Xu, C.#; Zhang, Y.#; Xu, K.; Nie, J.J.; Yu, B.; Li, S.; Cheng, G.; Li, Y*; Du, J.*; Xu, F. J.* Multifunctional cationic nanosystems for nucleic acid therapy of thoracic aortic dissection. Nature Communications. 2019, 10(1), 3184

(19)  Jin, X.#; Xiong, Y.#; Zhang, X.; Wang, R.; Xing, Y.; Duan, S.;* Chen, D.;* Tian, W.; Xu, F.J.* Self-adaptive antibacterial porous implants with sustainable responses for infected bone defect therapy. Advanced Functional Materials. 2019, 29(17): 1807915

(20)  Xu, F.J.* Versatile types of hydroxyl-rich polycationic systems via O-heterocyclic ring-opening reactions: from strategic design to nucleic acid delivery applications. Progress in Polymer Science. 2018, 78: 56-91