蔡 晴 教授

蔡   晴

教授/博导
生物材料系副主任
办公室:科技大厦811
E-mail:caiqing@mail.buct.edu.cn
研究团队:先进复合材料中心(acc.buct.edu.cn)

研究领域:
新型生物可降解高分子的设计/制备
骨/软骨组织工程支架材料
药物控释载体
硬组织修复材料

1989.9-1993.7,武汉大学,学士
1997.9-2000.7,中国科学院化学研究所,硕士
2000.9-2003.7,中国科学院化学研究所,博士

1993.7-1997.8,北京玻璃钢研究设计院,助理工程师
2013.1-2014.1,宾夕法尼亚州立大学,访问学者
2003.9-至今,北京化工大学材料科学与工程学院,讲师、副教授、教授

教学:本科生专业课程  《组织工程学》


荣誉与奖励:

2015,口腔硬组织修复高分子基生物医用材料及临床应用, 中国石油和化学工业联合会, 科技进步, 省部二等奖, 排名1/6
2015
,生物降解高分子材料多层次微结构的调控及其生物医学功能构筑, 教育部, 自然科学, 省部一等奖, 排名6/8
2014,
多尺度、多维度填料协同增强树脂基口腔生物材料及临床修复技术, 教育部, 技术发明, 省部二等奖, 排名5/6

2011, 入选教育部新世纪人才计划

 

科研项目:

1. 国家重点研发计划项目/课题,2017YFC1104300/4302,高值牙科修复材料/牙周再生材料,2017/07-2020/12,项目/课题负责人

2. 国家自然科学基金面上项目,51873013,基于纤维膜/细胞层构建梯度修复材料及其调控骨-软骨再生机制研究,2019/01-2022/12,项目负责人

3. 国家自然科学基金面上项目,51473016,磷酸钙基引导组织再生材料及其对成骨分化的影响研究,2015/01-2018/12,项目负责人

 

近期发表的部分论文:

1. Pengfei Wei, Zuoying Yuan, Jianping Mao, Qing Cai*, Xiaoping Yang. Bioresorable microspheres with surface-loaded nanosilver and apatite as dual-functional injectable cell carriers for bone regeneration. Macromol Rapid Comm, 2018, 39: 1800062.

2. Zhaohui Huang, Chenyuan Gao, Yiqian Huang, Xuehui Zhang, Xuliang Deng, Qing Cai*, Xiaoping Yang. An injectable polyphosphazene/gelatin hybrid hydrogel for biomedical applications. Mater & Design, 2018, 160: 1137-1147.

3. Chenyuan Gao, Zhaohui Huang, Wei Jing, Pengfei Wei, Le Jin, Xuehui Zhang*, Qing Cai*, Xuliang Deng, Xiaoping Yang. Directing osteogenic differentiation of BMSCs by cell-secreted decellularized extracellular matrixes from different cell types. J Mater Chem B2018, 6 7471-7485.

4. Zhiwei Ren, Shiqing Ma, Le Jin, Zihao Liu, Deping Liu, Xu Zhang, Qing Cai*, Xiaoping Yang*. Repairing bone defect with three-dimensional cellular construct composed of multi-layered cell sheet on electrospun mesh. Biofabrication, 2017, 9: 025036.

5. Zhaohui Huang, Pengfei Wei, Le Jin, Xiaoqing Hu, Qing Cai*, Xiaoping Yang*. Photoluminescent polyphosphazene nanoparticles for in situ simvastatin delivery to improve osteocompatibility of BMSCs. J Mater Chem B, 2017, 5: 9300-9311.

6. Siqi Zhu, Wei Jing, Xiaoqing Hu, Zirong Huang, Qing Cai*, Yingfang Ao, Xiaoping Yang*. Time-dependent effect of electrical stimulation on osteogenic differentiaon of bone mesenchymal stromal cells cultured on conductive nanofibers. J Biomed Mater Res A, 2017, 105: 3369-3383.

7. Ran Zhang, Deping Liu, Xiaolong Jia*, Qing Cai*, Xiaoping Yang. Nanoporous fibers built with carbon-bound SiO2 nanospheres via electrospinning and calcination. Mater & Design, 2017. 130: 231-238.

8. Zhaohui Huang, Lika Yang, Xuehuii Zhang, Bingyuan Ruan, Xiaoqing Hu, Xuliang Deng, Qing Cai*, Xiaoping Yang. Photoluminescent biodegradable polyphosphazenes for long-term in vivo tracking for tissue engineering application. Macromolecules, 2016, 49: 8508-8519.

9. Xiurui Zhang, Xiaoqing Hu, Xiaolong Jia, Lika Yang, Qingyang Meng, Yuanyuan Shi, Zhengzheng Zhang, Qing Cai*, Yingfang Ao*, Xiaoping Yang. Cell studies of hybridized carbon nanofibers containing bioactive glass nanoparticles using bone mesenchymal stromal cells. Sci Rep, 2016, 6: 38685.

10. Caijin Zhang, Man Cao, Jinle Lan, Pengfei Wei, Qing Cai*, Xiaoping Yang. Regulating proliferation and differentiation of osteoblasts on poly(l-lactide)/gelatin

11. Zhiwei Ren, Yang Wang, Shiqing Ma, Shun Duan, Xiaoping Yang, Ping Gao, Xu Zhang*, Qing Cai*. Effective bone regeneration using thermo-sensitive poly(N-isopropylacrylamide) grafted gelatin as injectable carrier for bone mesenchymal stem cells. ACS Appl Mater Interface, 2015, 7: 19006-19015.

12. Cuihua Zhang, Dan Cheng, Tianhong Tang, Xiaolong Jia*, Qing Cai*, Xiaoping Yang. Nanoporous structured carbon nanofiber/bioactive glass composites for skeletal tissue regeneration. J Mater Chem B, 2015, 3: 5300-5309.

13. Yougang Guo, Jinle Lan, Caijin Zhang, Man Cao, Qing Cai*, Xiaoping Yang. Mineralization on polylactide/gelatin composite nanofibers using simulated body fluid containing amino acid. Appl Surf Sci, 2015, 349: 538-548.

 

授权专利:

1. 蔡晴; 王杨; 任志伟; 杨小平, 一种明胶/聚酯共聚复合生物材料及其制备方法, 2017.8.25, 中国, ZL201410179040.7

2. 贾晓龙; 张翠华; 杨小平; 蔡晴; 唐天洪; 程丹, 一种具有生物活性的多孔杂化碳纳米纤维材料及其制备方法, 2016.5.11, 中国, ZL201410127601.9

3. 邓旭亮; 卫彦; 王莹; 张学慧; 蔡晴, 一种顺时释放成血管生长因子和成骨生长因子的亚微米核壳微球材料及其制备方法, 2015.7.15, 中国, ZL201410306449.0

4. 贾晓龙; 杨光; 杨小平; 李武胜; 蔡晴, 一种串珠状纳米纤维的制备方法, 2016.4.27, 中国, ZL201310638276.8

5. 杨小平; 滕瑜; 蔡晴; 李可雨; 段顺; 邓旭亮, 一种四氧化三铁磷酸钙核壳纳米磁性粒子及生物矿化法的制备方法, 2014.4.2, 中国, ZL201210057548.0

6. 蔡晴; 曹晓艳; 蔡绒; 杨小平; 毛吉富, 一种可注射聚膦腈/明胶复合水凝胶及其制备方法, 2012.10.17, 中国, ZL201110109276.X

7. 蔡晴; 杨小平; 邓旭亮; 周学刚; 张慎; 段顺, 引导组织再生膜及其制备方法, 2013.8.21, 中国, ZL201110006820.8