教授
办公室：化新楼B座213B
Email：dingxk@mail.buct.edu.cn
研究领域
生物医用材料是涉及材料学、生物学、组织工程学等多学科的交叉领域和研究前沿。伴随人类社会逐渐进入“后抗生素时代”，传统抗生素药物资源日益枯竭，因此开发新型抗菌功能化高分子材料并揭示其抗菌机制具有重要的科学意义和应用前景。另一方面，通过高分子材料的微图案化或多层次手性物质的精准构筑对调控细胞在生物医用材料表面的生理过程、揭示细胞与生物医用材料的相互作用机制具有重要指导意义。
主要研究方向如下：
（1）新型天然高分子抗菌材料的设计与构建；
（2）材料表面的抗菌功能化修饰及抗菌机理研究；
（3）材料表面的图案化及其与细胞的相互作用机制研究；
2000-2004：北京科技大学材料科学与工程系，学士
2005-2008：北京科技大学材料物理与化学系，硕士
2008-2014：新加坡国立大学化学与生物分子工程系，博士
2021 - 今：北京化工大学材料科学与工程学院，见习教授、教授
2014 - 2020：北京化工大学材料科学与工程学院，副教授
科研成果
主要从事生物医用材料的表界面功能化修饰，作为项目负责人主持国家自然科学基金项目4项，在国内外重要学术期刊发表SCI论文20余篇、授权专利3项。
代表性学术论文（10-15篇）
1.Wang, A.; Duan, S.; Ding, X.; Zhao, N.; Hu, Y.; Ding, X.*; Xu, F.-J.*, Bioswitchable Antibacterial Coatings Enable Self-Sterilization of Implantable Healthcare Dressings. Adv. Funct. Mater. 2021, 2011165.
2. Ding, X.; Duan, S. (co-first author); Ding, X.; Liu, R.*; Xu, F.-J.*, Versatile Antibacterial Materials: An Emerging Arsenal for Combatting Bacterial Pathogens. Adv. Funct. Mater. 2018, 28, 1802140.
3. Ding, X.; Wang, A.; Tong, W.; Xu, F.-J.*, Biodegradable Antibacterial Polymeric Nanosystems: A New Hope to Cope with Multidrug-Resistant Bacteria. Small 2019, 15, 1900999.
4. Lian, J.; Xu, H.; Duan, S.; Ding, X.; Hu, Y.; Zhao, N.; Ding, X.*; Xu, F.-J.*, Tunable Adhesion of Different Cell Types Modulated by Thermoresponsive Polymer Brush Thickness. Biomacromolecules 2020, 21, 732.
5. Tong, W.; Yao, X.; Duan, S.; Yu, B.; Ding, X.; Ding, X.*; Xu, F.-J.*, Gradient Functionalization of Various Quaternized Polyethylenimines on Microfluidic Chips for the Rapid Appraisal of Antibacterial Potencies. Langmuir 2020, 36, 354.
6. Tong, W.; Xiong, Y.; Duan, S.; Ding, X.*; Xu, F.-J.*, Phthalocyanine Functionalized Poly(Glycidyl Methacrylate) Nano-Assemblies for Photodynamic Inactivation of Bacteria. Biomater. Sci. 2019, 7, 1905.
7. Wu, X.; Ding, X.*; Xu, F.-J.*, Series of in Situ Photoinduced Polymer Graftings for Sensitive Detection of Protein Biomarkers Via Cascade Amplification of Liquid Crystal Signals. Biomacromolecules 2018, 19, 1959.
8. Wu, Y.; Nizam, M. N.; Ding, X.*; Xu, F.-J.*, Rational Design of Peptide-Functionalized Poly(Methacrylic Acid) Brushes for on-Chip Detection of Protease Biomarkers. ACS Biomater. Sci. Eng. 2018, 4, 2018.
9. Wu, Y.; Wang, A.; Ding, X.*; Xu, F.-J.*, Versatile Functionalization of Poly(Methacrylic Acid) Brushes with Series of Proteolytically Cleavable Peptides for Highly Sensitive Protease Assay. ACS Appl. Mater. Interfaces 2017, 9, 127.
10. Yuan, H.; Yu, B.; Fan, L.-H.; Wang, M.; Zhu, Y.; Ding, X.*; Xu, F.-J.*, Multiple Types of Hydroxyl-Rich Cationic Derivatives of Pgma for Broad-Spectrum Antibacterial and Antifouling Coatings. Polym. Chem. 2016, 7, 5709.
11. Huang, Y.; Ding, X. (co-first author); Qi, Y.; Yu, B.; Xu, F.-J., Reduction-Responsive Multifunctional Hyperbranched Polyaminoglycosides with Excellent Antibacterial Activity, Biocompatibility and Gene Transfection Capability. Biomaterials 2016, 106, 134.
12. Ding, X.; Yang, K. L., Antibody-Free Detection of Human Chorionic Gonadotropin by Use of Liquid Crystals. Anal. Chem. 2013, 85, 10710.
13. Ding, X.; Yang, K. L., Development of an Oligopeptide Functionalized Surface Plasmon Resonance Biosensor for Online Detection of Glyphosate. Anal. Chem. 2013, 85, 5727.
14. Ding, X.; Zhang, W.; Cheng, D.; He, J. Z.; Yang, K. L., Oligopeptides Functionalized Surface Plasmon Resonance Biosensors for Detecting Thiacloprid and Imidacloprid. Biosens. Bioelectron. 2012, 35, 271.
15. Ding, X.; Yang, K.-L., Liquid Crystal Based Optical Sensor for Detection of Vaporous Butylamine in Air. Sens. Actuators, B 2012, 173, 607.
专著
(1) Ding, X.; Yang, K.-L., Oligopeptides for Cancer and Other Biomedical Sensing Applications. In Next Generation Point-of-Care Biomedical Sensors Technologies for Cancer Diagnosis, Chandra, P.; Tan, Y. N.; Singh, S. P., Eds. Springer Singapore: Singapore, 2017, pp 279-304.
授权国家发明专利
1. 一种可视化检测蛋白质生物标志物的液晶传感器及其检测方法（ZL 201610827578.3）
2. 一种具有超声能力的医用导管的制备方法及其产品（ZL 201911099425.1）
3. 一种天然高分子与阳离子聚合物抗藻涂层玻璃的制备方法及其产品（ZL 201911099444.4）
